Related Experiment Video
Updated: Jun 18, 2026

Uncontrolled Hemorrhagic Shock Modeled via Liver Laceration in Mice with Real Time Hemodynamic Monitoring
Published on: May 21, 2017
Abstract:
The primary purpuras form a single clinical entity.Variations in the number of platelets can occur without the production of haemorrhages. These variations are the result of the condition of the capillaries and are not the cause of haemorrhages. The platelets may vary in any form of purpura, primary or secondary.The essential cause of the haemorrhagic state is a defect or increased permeability of the capillary endothelium.Purpura is allied to urticaria, the Henoch-Schönlein type being an intermediate state.
Related Concept Videos
Disorders of Hemostasis
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Hemorrhagic Stroke l: Introduction
Hemorrhagic Stroke ll: Pathophysiology
Introduction to Hemostasis
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized, and...
Anticoagulant Drugs: Low-Molecular-Weight Heparins
Extrinsic and Intrinsic Pathways of Hemostasis
The Extrinsic Pathway
The extrinsic pathway of coagulation is typically initiated by tissue damage that exposes blood to tissue factor (TF), a protein released by the damaged tissue cells outside the blood vessels—this interaction with TF triggers biochemical reactions involving specific clotting factors. The key player here is Factor VII, which forms a...
