Related Experiment Video
Updated: Jun 18, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
Seasonal disease variations depend on pathogen virulence, transmission, and host susceptibility. Climatic factors influence these primary elements, impacting disease "dispersability" and seasonal patterns, especially in autumnal infections.
Area of Science:
- Epidemiology
- Infectious Disease Dynamics
- Environmental Health
Background:
- Infectious disease spread is governed by pathogen factors, transmission routes, and host susceptibility.
- Climatic factors act as secondary influences, modulating these primary elements.
Purpose of the Study:
- To quantify the impact of secondary (climatic) factors on primary disease spread factors.
- To introduce and describe a measure of disease
- dispersability
- and its pre-epidemic relevance.
Main Methods:
- Investigated relationships between temperature, humidity, and various disease types (alimentary, respiratory, percutaneous, ectodermoses).
- Analyzed seasonal patterns, carrier influence, and cumulative effects of climatic changes on disease dispersability.
- Examined secular changes in seasonal disease periodicities and their association with disease spread dynamics.
Main Results:
- Identified specific relationships between climatic variables and disease types.
- Observed carrier-induced dispersability increases in spring and double-wave patterns.
- Highlighted cumulative effects of climate, particularly in autumnal infections, suggesting factors beyond direct temperature or light influence.
Conclusions:
- Climatic factors significantly alter disease dispersability through primary infection dynamics.
- Seasonal disease patterns, including complex autumnal trends, are influenced by cumulative climatic effects and potentially nutritional factors.
- Secular changes in disease periodicity reflect broader shifts in spread mechanisms and environmental interactions.
More Related Videos
05:08Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins
Published on: July 8, 2025
03:53Development of Multiplex Real-Time RT-qPCR Assays for the Detection of SARS-CoV-2, Influenza A/B, and MERS-CoV
Published on: November 10, 2023
Related Concept Videos
Infectious Diseases and Their Occurrence
Influenza
Malaria
Stages of Infection
Biological Clocks and Seasonal Responses
Introduction to Language of Pathophysiology ll