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Post-Operative Acidosis.

Proceedings of the Royal Society of Medicine

|December 9, 2009

Summary

This summary is machine-generated.

Anesthesia can cause mild acidosis and ketonuria, primarily due to tissue anoxia during surgery. While a high-carbohydrate diet may help, pre-existing acidosis requires careful management.

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Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring

Published on: December 14, 2020

Area of Science:

Anesthesiology
Biochemistry
Critical Care Medicine

Background:

Inhalation and local anesthetics can induce transient acidosis and ketonuria.
These metabolic disturbances are linked to compromised respiration and circulation during surgical procedures.

Purpose of the Study:

To investigate the occurrence and contributing factors of acidosis and ketonuria post-anesthesia.
To discuss the management of these conditions in both normal and diabetic patients, particularly in emergency settings.

Main Methods:

The study reviews the physiological effects of anesthesia on acid-base balance and ketone body production.
It examines the influence of pre-operative conditions and dietary interventions on post-anesthetic metabolic changes.

Main Results:

All inhalation anesthesias result in a slight but real acidosis and often ketonuria (20-80% of cases).
Local anesthetics cause similar, but less frequent and severe, effects.
Tissue anoxia from disrupted respiration/circulation is a primary cause; high-carbohydrate diets can mitigate but not eliminate acidosis.

Conclusions:

Post-anesthetic acidosis is a common, transient phenomenon in healthy individuals but can be exacerbated in those with pre-existing acidosis.
Pre- and post-operative management strategies are crucial for preventing complications, especially in diabetic patients and emergency cases.