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Updated: Jun 17, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Streptococcus pneumoniae meningo-encephalitis after trans-sphenoidal surgery: a case report
1Department of Neurology, Kirikkale University Faculty of Medicine, Kirikkale, Turkey. bulentbanrs@yahoo.com
Abstract:
Although meningismus or meningitis are known to occur after pituitary surgery; meningo-encephalitis caused by Streptococcus pneumoniae following a trans-sphenoidal approach has not been previously reported. A 56-year-old man presented with blurred vision. Two days after uneventful surgery, the patient became hyperpyrexic which progressed to confusion and lethargy within 48 hours. Spinal fluid cultures revealed Streptococcus pneumoniae. The patient was treated appropriately and made an uneventful recovery. MR images showed persistent changes within both frontal lobes. This case further suggests that peri-operative antimicrobial chemoprophylaxis may not save the patient from serious surgical infections.
Insights
A rare case of Streptococcus pneumoniae meningoencephalitis after pituitary surgery highlights infection risks. This suggests routine antibiotic prophylaxis may not prevent severe post-operative surgical infections.
Area of Science:
- Neurology
- Infectious Diseases
- Neurosurgery
Background:
- Meningismus and meningitis are known complications following pituitary surgery.
- Trans-sphenoidal surgery is a common approach for pituitary adenomas.
Observation:
- A 56-year-old male presented with blurred vision, post-trans-sphenoidal surgery.
- Within 48 hours, he developed hyperpyrexia, confusion, and lethargy.
Findings:
- Cerebrospinal fluid cultures confirmed Streptococcus pneumoniae meningitis.
- Magnetic resonance imaging revealed persistent frontal lobe changes.
Implications:
- This case represents the first reported instance of Streptococcus pneumoniae meningoencephalitis after trans-sphenoidal surgery.
- It questions the absolute efficacy of peri-operative antimicrobial chemoprophylaxis in preventing serious post-surgical infections.
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