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Updated: Jun 17, 2026
The Determination of Protease Specificity in Mouse Tissue Extracts by MALDI-TOF Mass Spectrometry: Manipulating PH to Cause Specificity Changes
Published on: May 25, 2018
Quantitative determination and localization of cathepsin D and its inhibitors
Alina Minarowska1, Alicja Karwowska, Marek Gacko
1Department of Clinical Nursing, Medical University of Bialystok, Bialystok, Poland. minar@mp.pl
Abstract:
A literature survey was performed of the methods of quantitative assessment of the activity and concentration of cathepsin D and its inhibitors. Usefulness of non-modified and modified proteins and synthetic peptides as measurement substrates was evaluated. The survey includes also chemical and immunochemical methods used to determine the distribution of cathepsin D and its inhibitors in cells and tissues.
