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A Novel Bayesian Change-point Algorithm for Genome-wide Analysis of Diverse ChIPseq Data Types
Published on: December 10, 2012
XBP1: the last two decades
1Department of Immunology and Infectious Diseases, Harvard School of Public Health, 651 Huntington Avenue, FXB 205, Boston, MA 02115, USA. lglimche@hsph.harvard.edu
Annals of the Rheumatic Diseases
|December 10, 2009
Abstract:
The transcription factor X box-binding protein 1 (XBP1) was isolated two decades ago in a search for regulators of major histocompatibility complex (MHC) class II gene expression. Many years of research finally revealed a protein with many functions, none of them related to the MHC. This paper provided an overview of what this multifunctional transcription factor actually does.
