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Association between bone mineral density and metabolic syndrome in postmenopausal Korean women
Kwan Kyu Park1, Sung-Jae Kim, Eun Su Moon
1Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea.
Background/Aims:
We investigated the relationship between bone mineral density (BMD) of the femur neck or lumbar spine and metabolic syndrome or its parameters in postmenopausal Korean women.
Methods:
This study included 399 postmenopausal women, for whom the BMD of their L2s-L4s and femur necks were examined in association with metabolic syndrome.
Results:
Subjects with metabolic syndrome had a higher BMD of the femur neck than those without metabolic syndrome when adjusted for age (0.85 +/- 0.09 vs. 0.82 +/- 0.12 g/cm(2), p = 0.011), while there was no statistical difference at lumbar spine. When adjusted for age and BMI, high-density lipoprotein cholesterol (HDL-C) was weakly and negatively correlated with BMD of the lumbar and femur neck (r = -0.107, p = 0.033; r = -0.111, p = 0.028 respectively).
Conclusion:
Metabolic syndrome was partly associated with higher BMD in our postmenopausal Korean women. Our study also showed that HDL-C levels were negatively associated with BMD of the lumbar spine and femur neck which means that subjects with lower HDL-C levels could have higher BMD. The results of our retrospective study revealed that metabolic syndrome could be associated with higher BMD in our postmenopausal Korean women.
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