Related Experiment Videos

Kawasaki disease presenting as parotitis in a 3-month-old infant

Hyun-Jeong Do1, Jong-Geun Baek, Hyun-Jung Kim

  • 1Department of Pediatrics, Institute of Health Science, Gyeongsang National University School of Medicine, Jinju, Korea.

Korean Circulation Journal
|December 10, 2009
PubMed

Insights

Antibiotic-resistant parotitis in infants may indicate Kawasaki disease, even without typical symptoms. Early diagnosis is crucial for timely treatment and preventing complications.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Cardiology

Background:

  • Kawasaki disease is a leading cause of acquired heart disease in children.
  • Parotitis is an uncommon but possible presentation of Kawasaki disease.
  • Mumps can present with parotitis, complicating differential diagnosis.

Purpose of the Study:

  • To highlight the importance of considering Kawasaki disease in infants with persistent, antibiotic-unresponsive parotitis.
  • To emphasize the diagnostic challenges when typical Kawasaki disease criteria are not met.

Main Methods:

  • Case report of a 3-month-old male infant with persistent fever and parotitis.
  • Serologic testing for mumps.
  • Clinical diagnosis of Kawasaki disease based on evolving features and echocardiography.

Main Results:

  • The infant presented with high fever and parotitis unresponsive to antibiotics.
  • Initial serology suggested mumps, but clinical and echocardiographic findings confirmed Kawasaki disease on day 9 of fever.
  • Diagnosis was established despite the absence of classic Kawasaki disease symptoms.

Conclusions:

  • Persistent, antibiotic-unresponsive parotitis in infants warrants consideration for Kawasaki disease.
  • Clinical vigilance and echocardiography are essential for diagnosing Kawasaki disease, especially in atypical presentations.
  • Early recognition of Kawasaki disease is critical for appropriate management and cardiovascular health.

Related Concept Videos

Poliomyelitis01:17

Poliomyelitis

Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
Rabies01:28

Rabies

Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Diphtheria01:28

Diphtheria

Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...