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The biology and clinical applications of granulocyte-macrophage colony-stimulating factor
K M Sakamoto1, D W Golde, J C Gasson
1Division of Hematology/Oncology, Children's Hospital, Los Angeles, CA 90027.
The Journal of Pediatrics
|March 1, 1991
Abstract:
GM-CSF is a hematopoietic growth factor that regulates myeloid cell proliferation and maturation and enhances the function of terminally differentiated effector cells. Results of clinical trials with GM-CSF in a number of disease states suggest a potential role of this growth factor to stimulate hematopoiesis. Future use of GM-CSF will depend on further studies to optimize its therapeutic efficacy.