Changes in diagnostic strategies for hilar-type Castleman's disease: report of two cases
Yuichi Sakairi1, Mitsutoshi Shiba, Kimitaka Kakizawa
1Department of General Thoracic Surgery, Kimitsu Central Hospital, 1010 Sakurai, Kisarazu, Chiba, 292-8535, Japan.
Insights
Castleman
Area of Science:
- Thoracic Surgery
- Diagnostic Pathology
Background:
- Castleman's disease (CD) is a rare lymphoproliferative disorder.
- Preoperative diagnosis of CD is challenging.
Observation:
- Two cases of hyaline vascular type CD are presented.
- Different preoperative diagnostic modalities were employed.
Findings:
- Thoracoscopic biopsy showed lymphatic structures suggestive of CD.
- Endobronchial ultrasound-guided transbronchial needle aspiration provided histological cores for diagnosis.
- Surgical resection confirmed the diagnosis in both cases.
Implications:
- Diverse minimally invasive techniques can aid in preoperative CD diagnosis.
- Accurate preoperative diagnosis can guide surgical planning and patient management.
- Further research into non-invasive diagnostic methods for CD is warranted.
Abstract:
Castleman's disease (CD) is rare and difficult to diagnose preoperatively. We report two similar cases of hyaline vascular type CD diagnosed preoperatively using different modalities. In the first case, a biopsy specimen taken during diagnostic thoracoscopy revealed lymphatic structure suggestive of CD. In the second case, endobronchial ultrasound-guided transbronchial needle aspiration enabled sampling of histological cores for histological diagnosis. In both cases, the final diagnosis was established by surgical resection.