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Updated: Jun 17, 2026

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit
Published on: April 15, 2021
[Coronary artery aneurysm with various clinical course]
A Morishima1, K Kaneda, Y Yoshida
1Department of Cardiovascular Surgery, Nara Hospital Kinki University School of Medicine, Ikoma, Japan.
Surgical repair is recommended for symptomatic coronary artery aneurysms (CAAs), including those causing angina, myocardial infarction, or rupture. Prompt intervention for large or complex CAAs ensures better patient outcomes.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Vascular Medicine
Background:
- Coronary artery aneurysms (CAAs) are abnormal dilations of the coronary arteries.
- While often asymptomatic, CAAs can lead to severe complications if left untreated.
Observation:
- This study presents four cases of patients with symptomatic CAAs.
- Symptoms included effort angina, dyspnea, general fatigue, and acute myocardial infarction.
- Diagnostic methods involved coronary angiography (CAG) and chest computed tomography.
Findings:
- Surgical interventions varied based on aneurysm characteristics, including coronary artery bypass grafting (CABG), patch angioplasty, fistula closure, and saphenous vein grafting.
- One case involved a ruptured CAA with pericardial effusion, necessitating urgent repair.
- Large aneurysms, defined as more than three times the normal diameter, were identified as a critical factor for surgical consideration.
Implications:
- These findings underscore the importance of timely surgical intervention for symptomatic and large coronary artery aneurysms.
- Effective management strategies can prevent life-threatening complications such as myocardial infarction and aneurysm rupture.
- The study highlights the diverse clinical presentations and successful surgical management of coronary artery aneurysms.
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