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08:03
Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Midline cervical cleft: a rare congenital anomaly
Gayathri Mandya Renukaswamy1, Marlene A Soma, Benjamin E J Hartley
1Department of Paediatric Otolaryngology, Great Ormond Street Hospital for Children National Health Service Trust, London, England.
The Annals of Otology, Rhinology, and Laryngology
|December 17, 2009
Summary
A midline cervical cleft (MCC) is a rare congenital neck defect. Surgical excision with Z-plasty repair is the recommended treatment for this condition.
Area of Science:
- Congenital Malformations
- Pediatric Surgery
- Developmental Biology
Background:
- A midline cervical cleft (MCC) is a rare congenital anomaly resulting from incomplete fusion of the first and second branchial arches.
- It presents as a midline anterior neck defect, potentially involving skin, sinus, or subcutaneous tissue.
Observation:
- This study reviewed 4 pediatric patients diagnosed with MCC.
- All patients exhibited an erythematous, fibrous band from chin to suprasternal notch.
Findings:
- Surgical management involved complete excision of the lesion and Z-plasty reconstruction.
- Histological findings and embryological origins were analyzed.
Implications:
- MCC should be considered in the differential diagnosis of midline cervical lesions in infants.
- Early surgical intervention with Z-plasty is crucial to prevent long-term complications.
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