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Updated: Jun 17, 2026

Protocol for Measuring the Thermal Properties of a Supercooled Synthetic Sand-water-gas-methane Hydrate Sample
Published on: March 21, 2016
Molecular cage occupancy of clathrate hydrates at infinite dilution: experimental determination and thermodynamic
Jiwoong Seol1, Jong-Won Lee, Do-Youn Kim
1Department of Chemical and Biomolecular Engineering (BK21 Program) and Gradute School of EEWS, Korea Advanced Institute of Science and Technology (KAIST), 373-1 Guseong-dong, Yuseong-gu, Daejeon 305-701, Republic of Korea.
Abstract:
This study focuses on the cage occupancy of guest molecules in the infinitely dilute state. At the extreme conditions of highly diluted guest concentrations the direct measurements of the cage occupancy ratio representing the competitive inclusion of multiguest species appear to be so difficult because of spectroscopic intensity limitation, but its thermodynamic significance might be considerable due to the fact that the infinite-dilution value of the cage occupancy ratio can provide the valuable thermodynamic information as a very unique and guest-specific parameter. To experimentally identify gaseous guest populations in structure I (sI) and structure II (sII) cages, we used the solid-state nuclear magnetic resonance (NMR), gas chromatography, and direct gas measurements. Furthermore, we derived the simple and generalized thermodynamic equation related to cage occupancies at infinite dilution from the van der Waals-Platteeuw model. Both experimental and predicted values agree well within the experimental error range.
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