Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 17, 2026

Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts

Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts

Published on: March 26, 2015

Can the Bio-Transfx pin fail during initial ACL graft insertion?

Alexander Golant¹, Eric J Strauss, Kevin Khajavi

¹Department of Orthopaedic Surgery, NYU School of Medicine, New York, New York, USA.

Bulletin of the NYU Hospital for Joint Diseases

|December 17, 2009

Summary

The Bio-Transfix pin shows high initial strength, exceeding surgeon forces in ACL reconstruction. Biodegradation or bone failure, not pin fracture, may cause early postoperative issues.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Knee Synovial Fluid Biomarker Type and Concentration With Long-Term Outcomes After ACL Reconstruction With Concomitant Meniscal Injury.

The American journal of sports medicine·2026

Same author

The Effect of Smoking History on Inflammatory Biomarkers in Synovial Fluid of Patients Undergoing Arthroscopic Knee Surgery for Meniscal Injury.

The American journal of sports medicine·2026

Same author

The Impact of Social Determinants of Health on Complications and Health Care Utilization After Tibial Tubercle Osteotomy.

Orthopaedic journal of sports medicine·2026

Same author

Surface-based treatment options for cartilage lesions of the knee.

Annals of joint·2026

Same author

Podium Abstracts Presented at the 2025 Annual Meeting of the Arthroscopy Association of North America.

Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association·2026

Same author

Podium Abstracts Presented at the 2025 Annual Meeting of the Arthroscopy Association of North America.

Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association·2026

Area of Science:

Orthopedic surgery
Biomaterials science
Biomechanics

Background:

The Bio-Transfix pin is a biodegradable implant for anterior cruciate ligament (ACL) graft fixation in the femoral tunnel.
Clinical observations suggest potential postoperative failure of this device.

Purpose of the Study:

To evaluate the initial mechanical strength of Bio-Transfix pin ACL fixations.
To compare fixation strength against forces generated during ACL graft tensioning by surgeons.

Main Methods:

Testing Bio-Transfix pin fixation strength in a simulated femoral tunnel model.
Measuring forces applied by five surgeons during simulated ACL graft tensioning.

Main Results:

Average pin strengths varied from 1075 N (10 mm tunnels) to 2160 N (8 mm tunnels).

Related Experiment Videos

Last Updated: Jun 17, 2026

Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts

Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts

Published on: March 26, 2015

Maximum forces generated by surgeons during tensioning were significantly lower, averaging 535 N.

Conclusions:

Initial pin fracture is improbable, as tested strengths far exceed surgeon-applied forces.
Potential causes for early fixation failure include supporting bone integrity issues or strength reduction from pin biodegradation.