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Updated: Jun 17, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
[Prevention and correction of cognitive disorders in arterial hypertension]
Insights
Preventing cognitive disorders in arterial hypertension (AH) patients involves managing cardiac and cerebral health. Certain medications like calcium antagonists offer advantages in preventing dementia and cognitive decline.
Area of Science:
- Cardiology
- Neurology
- Pharmacology
Context:
- Arterial hypertension (AH) is closely linked to cognitive impairment.
- Cardiac and cerebral pathologies often coexist in AH patients.
- Effective management of comorbidities is crucial for cognitive health in AH.
Purpose:
- To review and systematize literature on preventing and correcting cognitive disorders in arterial hypertension (AH).
- To highlight the interrelationship between cardiac and cerebral pathology in AH.
- To evaluate the role of antihypertensive therapy in preventing cognitive decline.
Summary:
- Multicenter randomized studies confirm a strong link between cardiac and cerebral pathology in AH patients.
- A rational approach to antihypertensive therapy and blood pressure (BP) management is vital, especially in high-risk individuals.
- Calcium antagonists, angiotensin II receptor blockers, and ACE inhibitors show advantages in preventing dementia and cognitive disturbances.
Impact:
- Provides evidence-based recommendations for antihypertensive drug selection in AH patients at risk of cognitive decline.
- Emphasizes the importance of integrated cardiovascular and neurological care for AH patients.
- Contributes to the prevention strategies for stroke and dementia in hypertensive populations.
Abstract:
In this review we systematized literature data illuminating problems of prevention and correction of cognitive disorders in patients with arterial hypertension (AH). On the basis of results of multicenter randomized studies we have demonstrated close interrelationship between cardiac and cerebral pathology and value of treatment of concomitant neurologic and cardiovascular disorders for prevention of cognitive disturbances in patients with AH. We have shown rational approach to planning antihypertensive therapy and to degree of arterial pressure (AP) lowering in patients with AH, including those with cerebrovascular pathology having high risk of development of stroke and dementia. It has been also shown that in patients with AH calcium antagonists, angiotensin II receptor blockers, and inhibitors of angiotensin converting enzyme posses definite advantages over antihypertensive drugs from other classes in prevention of dementia and less severe cognitive disturbances.
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