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Updated: Jun 17, 2026

Synthesis and Assay of Vibrio Quorum Sensing Inhibitors
Published on: May 31, 2024
Zoosporic plant pathogens produce bacterial autoinducer-2 that affects Vibrio harveyi quorum sensing
Ping Kong1, Bobby W K Lee, Zhaohui Sunny Zhou
1Department of Plant Pathology, Physiology and Weed Science, Virginia Polytechnic Institute and State University, Virginia Beach, VA 23455-3363, USA.
Abstract:
The frequent coisolation of bacteria with Phytophthora and Pythium species suggests possible interspecies communication. Zoospore-free fluids (ZFF) from bacteria-free and nutrient-depleted zoospore suspensions were examined to investigate the production of autoinducer-2 (AI-2), a bacterial interspecies signal molecule, by zoosporic oomycetes. ZFF from Phytophthora nicotianae, Phytophthora sojae, and Pythium aphanidermatum triggered luminescence of the Vibrio harve7yi AI-2 reporter, indicating the presence of AI-2 in zoospore extracellular products and the potential of cross-kingdom communication between oomycetes and bacteria. The production of AI-2 by zoospores was confirmed by chemical assays. These results provide a new insight into the physiology and ecology of oomycetes.
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