Guidelines for patient selection and performance of carotid artery stenting

    Insights

    Carotid artery stenting (CAS) is controversial, with carotid endarterectomy (CEA) being the benchmark. Guidelines recommend against CAS for most patients due to higher risks, emphasizing careful patient selection for carotid revascularization.

    Area of Science:

    • Vascular Surgery
    • Interventional Neurology
    • Medical Guidelines

    Background:

    • Carotid atherosclerosis treatment involves carotid artery stenting (CAS) and carotid endarterectomy (CEA).
    • CAS remains controversial, with CEA established as the benchmark for procedural safety and outcomes.
    • Existing guidelines highlight the need for careful patient selection for CAS.

    Purpose of the Study:

    • To develop consensus guidelines for the safe performance of CAS in Australasia.
    • To define patient selection criteria for CAS based on clinical and patho-anatomical factors.
    • To provide recommendations on the appropriate use of CAS versus CEA.

    Main Methods:

    • Modified Delphi consensus method involving iterative consultation among experts.
    • Review of randomized controlled trials and pooled analyses comparing CAS and CEA.
    • Consideration of evidence regarding distal protection devices and asymptomatic carotid stenosis.

    Main Results:

    • Randomized controlled trials indicate CAS is more hazardous than CEA.
    • CAS is not recommended for the majority of patients requiring carotid revascularization.
    • No evidence supports CAS for asymptomatic carotid stenosis; distal protection devices increase stroke risk.

    Conclusions:

    • CAS should not be the primary treatment for most patients needing carotid revascularization.
    • Strict patient selection, pre-procedural neuroimaging, and neurological assessment are critical for CAS.
    • Ongoing education, audit, and evidence review are necessary for maintaining CAS proficiency and updating guidelines.

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