Guidelines for patient selection and performance of carotid artery stenting
Insights
Carotid artery stenting (CAS) is controversial, with carotid endarterectomy (CEA) being the benchmark. Guidelines recommend against CAS for most patients due to higher risks, emphasizing careful patient selection for carotid revascularization.
Area of Science:
- Vascular Surgery
- Interventional Neurology
- Medical Guidelines
Background:
- Carotid atherosclerosis treatment involves carotid artery stenting (CAS) and carotid endarterectomy (CEA).
- CAS remains controversial, with CEA established as the benchmark for procedural safety and outcomes.
- Existing guidelines highlight the need for careful patient selection for CAS.
Purpose of the Study:
- To develop consensus guidelines for the safe performance of CAS in Australasia.
- To define patient selection criteria for CAS based on clinical and patho-anatomical factors.
- To provide recommendations on the appropriate use of CAS versus CEA.
Main Methods:
- Modified Delphi consensus method involving iterative consultation among experts.
- Review of randomized controlled trials and pooled analyses comparing CAS and CEA.
- Consideration of evidence regarding distal protection devices and asymptomatic carotid stenosis.
Main Results:
- Randomized controlled trials indicate CAS is more hazardous than CEA.
- CAS is not recommended for the majority of patients requiring carotid revascularization.
- No evidence supports CAS for asymptomatic carotid stenosis; distal protection devices increase stroke risk.
Conclusions:
- CAS should not be the primary treatment for most patients needing carotid revascularization.
- Strict patient selection, pre-procedural neuroimaging, and neurological assessment are critical for CAS.
- Ongoing education, audit, and evidence review are necessary for maintaining CAS proficiency and updating guidelines.
Abstract:
The endovascular treatment of carotid atherosclerosis with carotid artery stenting (CAS) remains controversial. Carotid endarterectomy (CEA) remains the benchmark in terms of procedural mortality and morbidity. Consensus Australasian guidelines for the safe performance of CAS were developed using the modified Delphi consensus method of iterative consultation. Selection of patients suitable for CAS needs careful consideration of clinical and patho-anatomical criteria. Randomised controlled trials and pooled analyses have demonstrated that CAS is more hazardous than CEA. The CGSC therefore recommends that CAS should not be performed in the majority of patients requiring carotid revascularisation. There is currently no evidence to support CAS as a treatment for asymptomatic carotid stenosis. The use of distal protection devices during CAS remains controversial with increased risk of clinically silent stroke. The knowledge requirements for the safe performance of CAS include an understanding of the evidence base from randomised controlled trials, carotid and aortic arch anatomy and pathology, and recognition and management of periprocedural complications. It is critical that all patients being considered for a carotid intervention have adequate pre-procedural neuroimaging and peri-procedural, independent, neurological assessment. Maintenance of proficiency in CAS requires active involvement in surgical/endovascular audit and continuing medical education programmes. These standards should apply in the public and private health-care settings. These guidelines represent the consensus of an intercollegiate committee in order to direct appropriate patient selection to perform CAS. Advances in endovascular technologies and the results of randomised controlled trials will guide future revisions of this document.
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