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Pulmonary Tuberculosis I

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
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Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
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Tuberculosis

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Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...

Pulmonary Tuberculosis V

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
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Pulmonary Tuberculosis II

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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
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Related Experiment Video

Updated: Jun 17, 2026

Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation

Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation

Published on: May 2, 2013

Tuberculosis following solid organ transplantation.

D Lopez de Castilla¹, N W Schluger

¹Department of Epidemiology and Environmental Health Sciences, Columbia University College of Physicians and Surgeons, Columbia University Medical Center, New York, New York 10032, USA.

Transplant Infectious Disease : an Official Journal of the Transplantation Society

|December 17, 2009

Summary

This summary is machine-generated.

Organ transplantation increases tuberculosis (TB) risk, especially for kidney transplant recipients and non-Caucasians. Early detection and prevention strategies are crucial for post-transplant patients to manage this serious complication.

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Area of Science:

Transplant medicine
Infectious diseases
Immunology

Background:

Organ transplantation significantly elevates patient risk for tuberculosis (TB).
TB presents diagnostic and treatment challenges in transplant recipients due to atypical presentations, high morbidity, and mortality.
Physicians face difficulties managing TB in immunocompromised transplant patients.

Purpose of the Study:

To determine the incidence of tuberculosis (TB) in solid organ transplant recipients.
To identify risk factors associated with the development of TB post-transplantation.
To compare TB incidence in transplant patients with the general population.

Main Methods:

A retrospective analysis of solid organ transplant recipients at a New York university medical center from 1988 to 2007.
Identification of patients who developed TB post-transplantation.
A nested case-control study comparing TB cases with control patients who did not develop TB, analyzing demographic and transplant-related factors.

Main Results:

Thirteen cases of TB were identified among 4925 transplants, yielding a cumulative incidence of 264/100,000.
Kidney transplant recipients (10 cases) and non-Caucasians showed a statistically significant increased risk for TB.
The median time to TB diagnosis post-transplant was 11.2 months.

Conclusions:

The incidence of TB in post-transplant patients is substantially higher than the general US background rate.
Kidney transplant recipients and non-Caucasian individuals are identified as high-risk groups for developing TB.
Prior exposure to TB may contribute to the increased risk in these specific patient populations.