Related Experiment Video
Updated: Jun 17, 2026

10:37
Transcranial Direct Current Stimulation (tDCS) for Memory Enhancement
Published on: September 18, 2021
Subjective memory decline in healthy community-dwelling elders. What does this complain mean?
Y Balash1, M Mordechovich, H Shabtai
1Tel-Aviv Sourasky Medical Center, Tel Aviv, Israel. yacbal@tasmc.health.gov.il
Acta Neurologica Scandinavica
|December 17, 2009
Summary
Subjective memory decline in healthy older adults is linked to early signs of depression, even without measurable cognitive impairment. This highlights the importance of considering mood in memory concerns.
Area of Science:
- Geriatric Psychology
- Cognitive Neuroscience
- Mental Health Research
Background:
- Subjective memory decline (SMD) is common in the elderly.
- Causes can be linked to affective and cognitive issues.
- Understanding the relationship between subjective and objective measures is crucial.
Purpose of the Study:
- To explore associations between subjective memory decline and cognitive/affective measures in healthy elderly individuals.
- To investigate the link between self-reported memory difficulties and clinical assessments.
Main Methods:
- Healthy subjects completed memory, lifestyle, depression (GDS), and anxiety questionnaires.
- Cognitive function was assessed using the Mini-Mental State Exam and NeuroTrax.
- Univariate logistic regression analyzed associations.
Main Results:
- 75.4% of participants reported subjective memory decline.
- No differences in demographics or lifestyle were found between groups.
- Subjective memory decline was associated with elevated Geriatric Depression Scale scores.
Conclusions:
- Subjective memory decline in healthy elderly individuals is associated with sub-clinical depression.
- This association exists even when objective cognitive decline is not present.
Related Concept Videos
Dementia
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual.
The progression of dementia is generally gradual.
Alzheimer Disease l: Introduction
Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
Dementia l: Introduction
Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
Cognitive Development During Adulthood
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
Drug Dosing: Geriatric Patients
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Negative and Cognitive Symptoms of Schizophrenia
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...

