Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cholecystitis01:20

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...
Gallbladder01:17

Gallbladder

The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins the common...
Cirrhosis II: Pathophysiology01:24

Cirrhosis II: Pathophysiology

Cirrhosis is a progressive chronic liver injury caused by prolonged inflammation, excessive fibrotic remodeling, and impaired regeneration. Over time, repeated hepatic insults disrupt the liver’s architecture and function, leading to reduced blood flow, impaired bile drainage, and diminished metabolic capacity.Pathophysiology of cirrhosisCirrhosis arises from three main responses to chronic liver damage: inflammation, immune activation, and hepatocyte death. These processes lead to structural...
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Cirrhosis I: Introduction01:23

Cirrhosis I: Introduction

Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ursodeoxycholic acid for the prevention of symptomatic gallstone disease after bariatric surgery (UPGRADE): a multicentre, double-blind, randomised, placebo-controlled superiority trial.

The lancet. Gastroenterology & hepatology·2021
Same author

Interpretation of laboratory results after gastric bypass surgery: the effects of weight loss and time on 30 blood tests in a 5-year follow-up program.

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery·2020
Same author

Risk Factors for Cholecystectomy After Laparoscopic Roux-En-Y Gastric Bypass.

Obesity surgery·2019
Same author

Gastrointestinal symptoms before and after laparoscopic Roux-en-Y gastric bypass: a longitudinal assessment.

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery·2019
Same author

A novel fully covered double-bump stent for staple line leaks after bariatric surgery: a retrospective analysis.

Surgical endoscopy·2018
Same author

Ursodeoxycholic acid for the prevention of symptomatic gallstone disease after bariatric surgery: study protocol for a randomized controlled trial (UPGRADE trial).

BMC gastroenterology·2017

Related Experiment Video

Updated: Jun 17, 2026

Laparoscopic Left Lateral Sectionectomy: Guided by the Ligamentum Teres Hepatis and the Umbilical Fissure Vein
03:33

Laparoscopic Left Lateral Sectionectomy: Guided by the Ligamentum Teres Hepatis and the Umbilical Fissure Vein

Published on: September 27, 2024

[Liver rupture caused by migrating gallstones].

Arnold W J M van de Laar1, Merel M Scheurkogel

  • 1Slotervaartziekenhuis, afd. Algemene Heelkunde, Amsterdam, The Netherlands. arnold.vandelaar@slz.nl

Nederlands Tijdschrift Voor Geneeskunde
|December 17, 2009
PubMed
Summary

Gallstones can cause rare but serious complications, including liver abscesses and rupture. This case highlights how gallstones can migrate, leading to severe abdominal issues and shock.

Area of Science:

  • Gastroenterology
  • Surgical Pathology

Background:

  • Gallstones (cholelithiasis) are common, but their migration through tissue layers is rare.
  • Chronic irritation from gallstones can lead to abscess formation.
  • Complications of gallstones can include liver abscesses and rupture.

Observation:

  • A 74-year-old man presented with abdominal pain, peritoneal irritation, and hemodynamic shock.
  • Emergency laparotomy revealed a liver abscess with a perforation.
  • A free-floating gallstone was discovered within the peritoneal cavity.

Findings:

  • The gallstone's migration path from the gallbladder to the liver was traceable.
  • The patient's symptoms correlated with the gallstone's progression and complications.
  • Liver abscess and rupture are rare sequelae of cholelithiasis.

Related Experiment Videos

Last Updated: Jun 17, 2026

Laparoscopic Left Lateral Sectionectomy: Guided by the Ligamentum Teres Hepatis and the Umbilical Fissure Vein
03:33

Laparoscopic Left Lateral Sectionectomy: Guided by the Ligamentum Teres Hepatis and the Umbilical Fissure Vein

Published on: September 27, 2024

Implications:

  • This case underscores the potential for severe intra-abdominal complications from gallstones.
  • Early recognition and management of gallstone disease are crucial to prevent such rare events.
  • Understanding gallstone migration pathways aids in diagnosing and treating complex presentations.