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Updated: Jun 17, 2026
23:06
The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
Published on: August 11, 2008
Drug-resistant tuberculosis in six hospitals in Rio de Janeiro, Brazil
R C Brito1, F C Q Mello, M K Andrade
1Programa de Controle da Tuberculose, Secretaria de Estado de Saúde e Defesa Civil do Rio de Janeiro, Rua México 128, Sala 411, Centro, Rio de Janeiro 20031 142, RJ, Brazil. rossanacb@terra.com.br
Summary
High rates of drug-resistant tuberculosis (TB) and multidrug-resistant TB (MDR-TB) were found in Rio de Janeiro. Hospitals may be a source of resistant TB transmission, necessitating urgent control measures.
Area of Science:
- Medical Research
- Infectious Diseases
- Public Health
Background:
- Tuberculosis (TB) remains a significant global health challenge, with drug resistance complicating treatment and control efforts.
- Estimating the burden of drug-resistant TB is crucial for effective public health strategies.
Purpose of the Study:
- To determine the prevalence of drug resistance (DR) and multidrug resistance (MDR) in TB patients in Rio de Janeiro.
- To identify factors associated with drug-resistant TB.
Main Methods:
- A cross-sectional survey was conducted over one year in six hospitals in Rio de Janeiro, Brazil.
- Data were collected from 595 patients, including those previously treated and not previously treated for TB.
Main Results:
- Overall, 17.1% of patients had drug-resistant TB and 7.4% had multidrug-resistant TB.
- Among previously treated patients, MDR-TB prevalence was 17.3%.
- Diagnosis in a TB reference hospital was associated with MDR-TB in both previously treated and untreated individuals.
Conclusions:
- High levels of drug-resistant and multidrug-resistant TB were observed in the study setting.
- Hospitals should be considered potential sites for the transmission of resistant TB strains.
- Urgent measures are needed to prevent nosocomial transmission of resistant TB.
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