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Updated: Jun 17, 2026

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease
Published on: August 24, 2019
Exercise capacity of children with pediatric lung disease
G S Zavorsky1, J R Kryder, S V Jacob
1Department of Obstetrics, Gynecology, and Women's Health, Saint Louis University, Saint Louis, MO 63117, USA. zavorsky@slu.edu
Insights
Children with cystic fibrosis (CF) and bronchopulmonary dysplasia (BPD) show similar peak exercise capacity, indicating mild pulmonary impairment does not affect exercise performance regardless of the condition's origin.
Area of Science:
- Pediatric Pulmonology
- Exercise Physiology
- Chronic Lung Disease
Background:
- Children with cystic fibrosis (CF) and bronchopulmonary dysplasia (BPD) exhibit similar resting pulmonary function despite different injury mechanisms.
- This study aimed to compare peak exercise responses between these groups.
Purpose of the Study:
- To compare peak exercise responses in children with BPD versus CF.
- To control for pulmonary impairment, nutritional status, gender, age, height, and predicted forced expired volume in 1 second.
Main Methods:
- Nine children with BPD and nine with CF participated.
- Participants underwent spirometry and a maximal progressive exercise test on a cycle ergometer.
Main Results:
- No significant differences were observed between groups in body mass percentile, peak power output (Wpeak), % predicted Wpeak, peak oxygen uptake (VO2peak), or % predicted VO2peak.
- Both groups achieved near-normal Wpeak and normal VO2peak.
Conclusions:
- Children with mild pulmonary impairments can achieve near-normal peak power output and normal VO2peak.
- The etiology or developmental onset of the lung condition does not appear to influence VO2peak or Wpeak.
Background:
Pulmonary function of children with cystic fibrosis (CF) and bronchopulmonary dysplasia (BPD) is similar at rest even though the mechanisms of injury differ. We sought to compare the peak exercise responses in children with BPD versus CF while controlling for pulmonary impairment, nutritional status, gender, age, height, and predicted forced expired volume in 1 second (approximately 73% of predicted).
Methods:
Nine BPD children and 9 CF children underwent spirometry and a progressive exercise test to maximum on a cycle ergometer.
Results:
There was no difference between groups in body mass percentile (CF:97 +/- 13%, BPD: 98 +/- 11%), peak power output (Wpeak) (CF:67 +/- 19 W, BPD:73 +/- 28 W), % predicted Wpeak (CF:83 +/- 28%, BPD:88 +/- 15%), peak oxygen uptake (VO2peak, CF: 38 +/- 7 ml/kg/min, BPD: 39 +/-6 ml/kg/min), or % predicted VO2peak (CF:99 +/- 16 %, BPD:96 +/- 27%).
Conclusions:
Children with mild pulmonary impairments are able to achieve a near normal peak power output and a normal VO2peak. Neither the aetiology nor the developmental onset of the process appears to be important influences on VO2peak or Wpeak.
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