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Updated: Jun 17, 2026

An Efficient and Simple Method to Establish NK and T Cell Lines from Patients with Chronic Active Epstein-Barr Virus Infection
Published on: March 30, 2018
[Lymphoid hemopathies and HHV-8]
Véronique Meignin1, Lionel Galicier
1Service d'anatomie pathologique, hôpital Saint-Louis, AP-HP, Paris cedex 10, France. veronique.meignin@sls.aphp.fr
Abstract:
HHV-8 is a gamma herpes virus described for the first time in humans in 1994 within Kaposi's disease cells. Since, it has been found to be involved in lymphoïd proliferative disorders. First, it has been described in multicentric Castleman's disease (100 % of HIV infected patients and 50 % of HIV negative patients), in multicentric Castleman's disease associated lymphomas and in cavitary and extracavitary primary effusion lymphomas (100 % of cases). More recently, some other HHV-8 associated lymphoproliferations have been described. We describe in this review the characteristics of this virus, along with the clinical, pathological and molecular characteristics of the different entities associated with HHV-8.
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