Giant, solid, invasive prolactinoma in a prepubescent boy with gynecomastia

Area of Science:

• Pediatric Endocrinology
• Neuro-oncology
• Tumor Biology

Background:

• Pituitary adenomas are rare in prepubescent children, often presenting as functioning tumors.
• Presentation can include visual disturbances and morphological changes due to tumor mass effect.

Observation:

• A case of a giant, solid, invasive prolactinoma in a 7-year-old boy is presented.
• The patient exhibited visual disturbances and gynecomastia.

Findings:

• Subtotal tumor decompression and 4 months of oral bromocriptine led to significant vision improvement and tumor size reduction.
• Dopamine agonist therapy and surgical decompression are standard treatments for pediatric prolactinomas.

Implications:

• This case highlights successful management of a rare pediatric pituitary tumor.
• Early diagnosis and multimodal treatment are crucial for favorable outcomes in children with giant prolactinomas.