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Acute zonal occult outer retinopathy: a case report.
Josephine O Ibironke1, Andrew S Gurwood
1The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA. jibiron1@jhmi.edu
Optometry (St. Louis, Mo.)
|December 17, 2009
Summary
Acute zonal occult outer retinopathy (AZOOR) is a rare retinal disorder affecting young women. This case highlights AZOOR
Area of Science:
- Ophthalmology
- Retinal Diseases
- Neuro-ophthalmology
Background:
- Acute zonal occult outer retinopathy (AZOOR) is an idiopathic retinal disorder.
- It affects young women, causing acute outer retinal dysfunction and visual field loss.
- Symptoms include photopsia, variable funduscopic changes, and abnormal electroretinograms (ERGs).
Observation:
- A 24-year-old woman presented with acute photopsia and temporal vision clouding in her right eye.
- Progression showed deep chorioretinal involvement and an anterior chamber response.
- An afferent pupillary defect (APD) and retinal pigment epithelium (RPE) changes developed over time.
Findings:
- AZOOR diagnosis was confirmed after extensive testing.
- The condition showed remission at 21 and 31 months post-diagnosis.
- Persistent dense inferior-temporal visual field defect remained despite symptom resolution.
Implications:
- AZOOR diagnosis can be challenging due to subtle and vague presentations.
- Understanding AZOOR's clinical course, presentation, and etiology is crucial.
- This case underscores the importance of thorough evaluation for accurate AZOOR diagnosis and management.
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