Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 17, 2026

Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

Radiosurgery for craniopharyngioma.

Ajay Niranjan1, Hideyuki Kano, David Mathieu

  • 1Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA. niranjana@upmc.edu

International Journal of Radiation Oncology, Biology, Physics
|December 17, 2009
PubMed
Summary

Gamma knife stereotactic radiosurgery (SRS) offers a safe and effective treatment for residual or recurrent craniopharyngiomas. Achieving complete radiosurgical coverage of the tumor is key to optimizing tumor control rates.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dual AI models for gamma knife radiosurgery in craniopharyngioma: prescription dose modeling and outcome risk prediction.

Journal of neuro-oncology·2026
Same author

Machine learning prediction of local control after Gamma Knife radiosurgery to post-resection cavities from brain metastases: a proof-of-concept study.

Journal of neuro-oncology·2026
Same author

Therapeutic Hybrid Intelligence with Neural and Knowledge-based Expert Reasoning for SRS (THINKERS): an AI model for GBM.

Journal of neuro-oncology·2026
Same author

Dose De-escalation in Stereotactic Radiosurgery for Melanoma Brain Metastases in Patients on Concurrent Immunotherapy or Targeted Therapy: A Multicenter Experience.

Neurosurgery·2026
Same author

Beyond tumor control: symptom trajectories and hearing outcomes after contemporary Gamma Knife radiosurgery for vestibular schwannoma.

Journal of neuro-oncology·2026
Same author

Therapeutic Hybrid Intelligence with Neural and Knowledge-based Expert Reasoning for SRS (THINKERS): a mixture-of-experts AI model for vestibular schwannoma.

Journal of neuro-oncology·2026

Area of Science:

  • Neurosurgery
  • Radiation Oncology
  • Oncology

Background:

  • Craniopharyngiomas are rare tumors that can recur or persist after initial treatment.
  • Stereotactic radiosurgery (SRS) presents a minimally invasive therapeutic option for these challenging cases.

Purpose of the Study:

  • To evaluate the efficacy of Gamma Knife stereotactic radiosurgery (SRS) for residual or recurrent craniopharyngiomas.
  • To identify prognostic factors influencing tumor control rates after SRS.

Main Methods:

  • A retrospective analysis of 46 patients with craniopharyngiomas treated with 51 SRS procedures.
  • Median tumor volume, prescription dose, and maximal dose were recorded.
  • Mean follow-up duration was 62.2 months.

More Related Videos

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy
11:24

Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy

Published on: October 18, 2011

Related Experiment Videos

Last Updated: Jun 17, 2026

Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy
11:24

Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy

Published on: October 18, 2011

Main Results:

  • Overall survival rate was 97.1% at 5 years.
  • Progression-free survival (solid tumor control) was 91.6% at both 3 and 5 years.
  • Local control rates were 91%, 81%, and 68% at 1, 3, and 5 years, respectively. Complete radiosurgical coverage was a significant favorable prognostic factor.

Conclusions:

  • Gamma Knife SRS is a safe and effective treatment for residual or recurrent craniopharyngiomas.
  • Complete radiosurgical coverage is associated with improved tumor control outcomes.