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Updated: Jun 17, 2026

Transesophageal Atrial Burst Pacing for Atrial Fibrillation Induction in Rats
Published on: February 14, 2022
Termination of drug-induced torsades de pointes with overdrive pacing
Nathan P Charlton1, David T Lawrence, William J Brady
1Department of Emergency Medicine, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.
Abstract:
Drug-induced prolongation of the QT interval is frequently encountered after medication overdose. Such toxicity can result in degeneration to torsades de pointes (TdP) and require overdrive pacing. We present 3 cases in which intentional medication overdose resulted in QTc prolongation with subsequent degeneration to TdP. Despite appropriate care, including magnesium therapy, each case required overdrive pacing for resolution of TdP. Although rarely encountered, patients with drug-induced TdP can be successfully managed with overdrive pacing.
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