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Spread of subarachnoid sensory block with hyperbaric bupivacaine in second trimester of pregnancy
Guie Y Lee1, Chi H Kim, Rack K Chung
1Department of Anesthesiology and Pain Medicine, School of Medicine, Ewha Womans University Mokdong Hospital, Seoul, Korea. lgyanes@ewha.ac.kr
Study Objective:
To compare the spread of subarachnoid sensory block with hyperbaric bupivacaine in second trimester pregnant and non-pregnant women.
Design:
Prospective study.
Setting:
University teaching hospital.
Patients:
44 ASA physical status I and II women patients, 22 of whom were in their second trimester of pregnancy undergoing cervical cerclage, and 22 non-pregnant women scheduled for perianal surgery.
Interventions:
The extent of sensory block and hemodynamic changes were assessed.
Measurements:
Number of dermatomes blocked was determined by testing for pinprick; systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were measured at 3, 5, 10, 15, 30 and 60 minutes.
Main Results:
Maximal sensory block was higher in the second trimester of the pregnant group by three dermatomes than the non-pregnant group. There were no statistically significant differences in SBP, DBP, or HR changes between the groups.
Conclusion:
Pregnant women in the second trimester exhibit enhanced spread of spinal analgesia with hyperbaric bupivacaine more so than non-pregnant women.
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