Related Experiment Video
Updated: Jun 17, 2026

Expanding the Toolkit for In Vivo Imaging of Axonal Transport
Published on: December 23, 2021
Fast intra-axonal transport: Beginning, development and post-genome advances
1Hults Gata 98, S-436 44 ASKIM Gothenburg-Askim, Sweden. annica.dahlstrom@anatcell.gu.se
Abstract:
The review describes the initial experiments suggesting a fast intra-axonal transport of transmitter related substances, in addition to the "classic" slow flow. Early experiments were mainly conducted in the peripheral adrenergic system, focusing on transport of amine storage granules, the extent of the vast sympathetic adrenergic system and the importance of axonal transport of amine granules for the adrenergic system. Further, it describes important advances obtained from studies of other neuron systems regarding local axonal protein synthesis, motor proteins and new insights regarding relation between faults in the transport machinery and some neuropathological conditions.
Related Concept Videos
Neurons: The Axon
The axon attaches to the cell body at a cone-shaped elevation called the axon hillock. The initial part of the axon, closest to the hillock, is known as the initial segment.
The Movement of Organelles and Vesicles
Microtubule Associated Motor Proteins
Assembly of Complex Microtubule Structures
Intracellular Movement of Viruses and Bacteria
Spindle Assembly
In most cells, centrosomes are the primary microtubule nucleation centers. In the centrosome-mediated pathway, the G2-prophase transition triggers centrosome maturation and increased microtubule nucleation. Progressive nucleation results in a microtubule array...