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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Renal Failure: Dose Adjustments01:11

Renal Failure: Dose Adjustments

In patients with renal impairment, drugs undergo significant changes in their pharmacokinetics, which require dosage adjustments to ensure safe and effective therapy.
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...

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Related Experiment Video

Updated: Jun 17, 2026

Murine Renal Transplantation Procedure
18:48

Murine Renal Transplantation Procedure

Published on: July 10, 2009

Kidney transplantation in the elderly.

Edmund Huang1, Dorry L Segev, Hamid Rabb

  • 1Department of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.

Seminars in Nephrology
|December 17, 2009
PubMed
Summary
This summary is machine-generated.

Kidney transplantation offers significant benefits for the older population with end-stage renal disease, improving survival and quality of life compared to dialysis. Careful consideration of various factors is crucial for successful elderly kidney transplants.

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Last Updated: Jun 17, 2026

Murine Renal Transplantation Procedure
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11:47

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Orthotopic Kidney Auto-Transplantation in a Porcine Model Using 24 Hours Organ Preservation And Continuous Telemetry
07:58

Orthotopic Kidney Auto-Transplantation in a Porcine Model Using 24 Hours Organ Preservation And Continuous Telemetry

Published on: August 21, 2020

Area of Science:

  • Nephrology
  • Geriatric Medicine
  • Transplant Surgery

Background:

  • Increasing prevalence of end-stage renal disease (ESRD) in the older population in the United States.
  • Parallel rise in kidney transplantation rates among elderly individuals.
  • ESRD necessitates renal replacement therapy, with transplantation being a key option.

Purpose of the Study:

  • To review kidney transplantation in elderly patients.
  • To discuss access, outcomes, and ethical considerations for elderly kidney transplant recipients.
  • To highlight the benefits of transplantation over dialysis for this demographic.

Main Methods:

  • Literature review focusing on kidney transplantation in older adults.
  • Analysis of factors influencing transplant outcomes in the elderly.
  • Discussion of immunological, physiological, and psychosocial aspects.

Main Results:

  • Older kidney transplant recipients have lower patient survival than younger recipients but still benefit from reduced mortality and improved quality of life compared to dialysis.
  • Donor quality significantly impacts transplant outcomes.
  • Immunological, physiological, and psychosocial factors are critical for successful transplantation in the elderly.

Conclusions:

  • Kidney transplantation is a viable and beneficial treatment for elderly patients with ESRD.
  • Addressing specific challenges related to aging, donor quality, and allocation schemes is essential.
  • Multifaceted care is required to optimize outcomes for elderly kidney transplant recipients.