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Dendritic cells transmit HIV-1 through human small intestinal mucosa

Ruizhong Shen1, Lesley E Smythies, Ronald H Clements

  • 1Departmentsof Medicine (Gastroenterology), University of Alabama at Birmingham, Birmingham, AL 35294-2182, USA.

Journal of Leukocyte Biology
|December 17, 2009
PubMed
Summary

Dendritic cells (DCs) in the small intestine transport HIV-1 through the mucosa. These intestinal DCs facilitate the transmission of the human immunodeficiency virus type 1 (HIV-1) to lymphocytes, contributing to mother-to-child transmission.

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