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Clinical and epidemiological characteristics of children with Kawasaki disease in Turkey
Halil Ozdemir1, Ergin Ciftçi, Anil Tapisiz
1Department of Pediatrics, Ankara University Medical School, Dikimevi, Ankara, Turkey. doktorhalil@gmail.com
Insights
Kawasaki disease (KD) in Turkish children often presents with fever and characteristic symptoms like conjunctivitis. A significant 33.3% of patients developed coronary artery abnormalities, highlighting the need for early diagnosis.
Area of Science:
- Pediatrics
- Cardiology
- Epidemiology
Background:
- Kawasaki disease (KD) is a primary cause of acquired heart disease in children.
- Understanding KD's clinical and epidemiological profile in diverse populations is crucial.
Purpose of the Study:
- To detail the clinical and epidemiological features of Kawasaki disease in a Turkish pediatric cohort.
- To assess the incidence of coronary artery abnormalities in children diagnosed with KD in Turkey.
Main Methods:
- Retrospective review of medical records for 24 pediatric patients diagnosed with KD.
- Data collected from Ankara University Medical School, Turkey, between January 1994 and June 2009.
Main Results:
- The study included 24 patients, with a male-to-female ratio of 1.4:1 and a median age of 2 years.
- Common symptoms included conjunctivitis, oral changes (87.5%), cervical lymphadenopathy (70.8%), and rash (66.7%).
- Coronary artery abnormality (CAA) was observed in 33.3% of cases, irrespective of complete or incomplete KD diagnosis.
Conclusions:
- Kawasaki disease should be considered in the differential diagnosis for infants presenting with prolonged fever.
- Prompt recognition and management are vital to mitigate risks, including coronary artery abnormalities.
Background:
Kawasaki disease (KD) is the leading cause of acquired heart disease in childhood in the developed countries. The objective of this study is to describe the clinical and epidemiological characteristics of children with KD in Turkey.
Methods:
The medical records of 24 patients treated for KD between January 1994 and June 2009 at Ankara University Medical School, Turkey were reviewed.
Results:
The male-to-female ratio was 1.4 : 1. The median age at diagnosis was 2 years (range: 6.5 months to 11 years). Conjunctivitis and changes in the lips and oral cavity were seen in 21/24 (87.5%), cervical lymphadenopathy 17/24 (70.8%), polymorphous rash 16/24 (66.7%) and peripheral changes in 12/24 (50%). Coronary artery abnormality (CAA) was observed in 8/24 (33.3%) cases. CAA was seen in both the complete and incomplete groups with similar frequency (31.3% vs. 37.5%, respectively).
Conclusions:
KD must be kept in mind in the differential diagnosis of infants with prolonged fever.
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