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Thrombus in the distal aortic arch after apicoaortic conduit for severe aortic stenosis
Shinsuke Kotani1, Koji Hattori, Yasuyuki Kato
1Department of Cardiovascular Surgery, Osaka City General Hospital, Miyakojima, Osaka, Japan. m1155424@med.osaka-cu.ac.jp
Insights
Thrombogenesis occurred in the aortic arch after apicoaortic conduit surgery despite warfarin. Immediate anticoagulation is recommended post-surgery to prevent blood clots, even with bioprosthetic valves.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Medical Imaging
Background:
- Severe aortic stenosis (AS) often necessitates surgical intervention.
- Apicoaortic conduit (AAC) surgery is an alternative for patients with complex aortic calcification.
- Bioprosthetic valves are commonly used in AAC procedures.
Observation:
- A 71-year-old woman developed a distal aortic arch thrombus post-AAC surgery for severe AS.
- Computed tomography (CT) and cine magnetic resonance imaging (MRI) confirmed the thrombus and indicated blood flow stagnation.
- The thrombus significantly reduced in size by six months post-surgery.
Findings:
- Apicoaortic conduit surgery can lead to thrombogenesis in the aortic arch, potentially due to altered blood flow dynamics.
- Blood flow patterns may evolve over time following AAC procedures.
- Delayed antegrade flow through the native aortic valve was observed one year post-surgery.
Implications:
- Early initiation of postoperative anticoagulant therapy is crucial, irrespective of bioprosthetic valve use.
- Close monitoring for thrombotic events is warranted after AAC surgery.
- Understanding blood flow changes post-AAC is vital for optimizing patient management and preventing complications.
Abstract:
We report an uncommon case of thrombogenesis in the distal aortic arch after apicoaortic conduit (AAC) for severe aortic stenosis (AS). A 71-year-old woman underwent AAC with a bioprosthetic valve for severe AS because of heavy calcification of the ascending aorta. Although anticoagulant therapy with warfarin was performed, a postoperative computed tomographic (CT) scan revealed a thrombus in the distal aortic arch. Cine magnetic resonance imaging (MRI) revealed stagnation of the blood flow at that site. Administration of warfarin was continued. A follow-up CT-scan showed a marked reduction of the thrombus at six months after the surgery. A follow-up MRI revealed that the antegrade flow through the native aortic valve was decreased at one year after the surgery. We suggest that thrombogenesis may occur after AAC because of stagnation of the blood flow and that the distribution of the blood flow may change during the follow-up period. Therefore, we recommend that postoperative anticoagulant therapy should be initiated immediately, even when a bioprosthetic valve is used.
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