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Related Concept Videos

Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
Human Genetics01:28

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
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Synteny and Evolution02:31

Synteny and Evolution

John H. Renwick first coined the term “synteny” in 1971, which refers to the genes present on the same chromosomes, even if they are not genetically linked. The species with common ancestry tend to show conserved syntenic regions. Therefore, the concept of synteny is nowadays used to describe the evolutionary relationship between species.
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Genetic Variation01:25

Genetic Variation

Genetic variation is the diversity in DNA sequences found among individuals of the same species. This diversity is crucial for a species' survival because it helps organisms adapt to environmental changes. Genetic variation begins with fertilization, where an egg and sperm cell merge. Each of these cells carries 23 chromosomes, up to 46 in the fertilized egg. Chromosomes are long DNA strands that contain genes, the basic units of heredity.
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What is Population Genetics?01:25

What is Population Genetics?

A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.While some alleles of a given gene might be observed commonly, other variants...
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes
08:35

Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes

Published on: July 17, 2021

Mapping human genetic diversity in Asia.

, Mahmood Ameen Abdulla, Ikhlak Ahmed

    Science (New York, N.Y.)
    |December 17, 2009
    PubMed
    Summary
    This summary is machine-generated.

    Genetic variation in Asia strongly correlates with language and geography. Southeast Asia was a primary source for East Asian populations, showing a north-south diversity gradient.

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    Published on: August 12, 2019

    Area of Science:

    • Human population genetics
    • Genomics
    • Anthropology

    Background:

    • Asia's vast genetic diversity is poorly understood.
    • Previous studies lacked comprehensive geographic sampling.

    Observation:

    • A large-scale survey of Asian populations was conducted.
    • Autosomal genetic variation was analyzed across diverse geographic regions.

    Findings:

    • Genetic ancestry aligns with linguistic affiliations and geography.
    • Most populations exhibit intra-group relatedness despite gene flow.
    • East Asian haplotypes are largely present in Southeast and Central-South Asian populations, indicating a south-to-north decrease in diversity.

    Implications:

    • Southeast Asia is identified as a significant source for East Asian genetic makeup.
    • Understanding Asian population history requires considering both geography and language.
    • This study provides a framework for future research on human migration and adaptation in Asia.