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Blood Transfusion

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
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Coagulation

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Blood Transfusion and Agglutination

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Anticoagulant Drugs: Low-Molecular-Weight Heparins

Anticoagulant Drugs: Low-Molecular-Weight Heparins

Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...

Introduction to Hemostasis

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Updated: Jun 17, 2026

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time

Published on: February 14, 2017

Point-of-care coagulation testing and transfusion algorithms.

L J Enriquez¹, L Shore-Lesserson

¹Montefiore Medical Center, Department of Anesthesiology, Bronx, NY, USA.

British Journal of Anaesthesia

|December 17, 2009

Summary

This summary is machine-generated.

Cardiovascular patients often have bleeding risks and require monitoring of coagulation. This review covers essential monitoring tools for heparin, platelet function, and anti-platelet drugs during cardiac surgery.

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Last Updated: Jun 17, 2026

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time

Published on: February 14, 2017

The Nijmegen Hemostasis Assay: Simultaneous Fluorogenic Measurement of Thrombin and Plasmin Generation in a Single Well

The Nijmegen Hemostasis Assay: Simultaneous Fluorogenic Measurement of Thrombin and Plasmin Generation in a Single Well

Published on: February 27, 2026

Area of Science:

Cardiovascular Medicine
Hematology
Anesthesiology

Background:

Patients with cardiovascular disease (CVD) exhibit hemostasis disorders, increasing risks of thrombosis and embolism.
These patients frequently use anti-thrombotic medications to prevent adverse cardiovascular events.
Cardiac surgery patients present complex hemostatic challenges due to underlying conditions, medications, and cardiopulmonary bypass.

Purpose of the Study:

To review available perioperative coagulation monitoring systems.
Emphasis is placed on monitoring relevant to cardiovascular surgery.
To discuss specific monitors for heparin, platelet function, and anti-platelet agents.

Main Methods:

Literature review of perioperative coagulation monitoring techniques.
Focus on monitoring strategies applicable to cardiac surgery.
Discussion of heparin assays, platelet function tests, and anti-platelet drug monitoring.

Main Results:

Various monitoring tools exist for perioperative coagulation management.
Heparin monitoring is crucial for patients on anticoagulation.
Platelet function monitoring aids transfusion decisions, and anti-platelet drug monitoring is vital.

Conclusions:

Effective perioperative coagulation monitoring is essential for patients with CVD undergoing cardiac surgery.
Utilizing appropriate monitoring tools can mitigate bleeding risks and improve patient outcomes.
The review highlights key monitors for heparin, platelet function, and anti-platelet therapies.