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Related Concept Videos

Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
Fetal Circulation01:14

Fetal Circulation

Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
Disorders of Hemostasis01:24

Disorders of Hemostasis

Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...

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Related Experiment Video

Updated: Jun 17, 2026

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas
05:31

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas

Published on: January 26, 2024

Maternal haemorrhage.

M Walfish1, A Neuman, D Wlody

  • 1SUNY Downstate Medical Center, 450 Clarkson Ave., Box 6, Brooklyn, NY 11203, USA. menachem.walfish@downstate.edu

British Journal of Anaesthesia
|December 17, 2009
PubMed
Summary
This summary is machine-generated.

Maternal hemorrhage, a leading cause of preventable death, requires prompt management including hemodynamic stabilization and advanced interventions. Early detection and multidisciplinary care improve outcomes for severe postpartum bleeding.

More Related Videos

Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus
06:55

Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus

Published on: December 5, 2015

Related Experiment Videos

Last Updated: Jun 17, 2026

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas
05:31

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas

Published on: January 26, 2024

Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus
06:55

Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus

Published on: December 5, 2015

Area of Science:

  • Obstetrics and Gynecology
  • Maternal Health
  • Critical Care Medicine

Background:

  • Maternal hemorrhage is the primary cause of preventable maternal mortality globally.
  • It encompasses bleeding during pregnancy, labor, and postpartum.
  • Despite advances, unexpected severe bleeding remains a critical concern.

Purpose of the Study:

  • To review factors predisposing to severe maternal bleeding.
  • To highlight current management strategies and recent guidelines.
  • To discuss novel treatments for intractable postpartum hemorrhage.

Main Methods:

  • Literature review of factors, diagnostics, and management of maternal hemorrhage.
  • Analysis of current treatment algorithms and guidelines.
  • Evaluation of recent advancements in interventional radiology and pharmacotherapy.

Main Results:

  • Prenatal care and tertiary center referral improve management of high-risk patients.
  • Hemodynamic stabilization via IV access, monitoring, and transfusion is the first step.
  • Minimally invasive techniques like embolization and arterial ligation offer conservative management options.
  • Hysterectomy remains an option for intractable bleeding, with recombinant factor VIIa as a potential treatment for coagulopathy.

Conclusions:

  • A systematic algorithmic approach combining medical and surgical interventions is crucial.
  • Advanced techniques aim to preserve fertility by avoiding hysterectomy when possible.
  • Prompt and aggressive management is key to reducing maternal morbidity and mortality from hemorrhage.