Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Biological Clocks and Seasonal Responses02:45

Biological Clocks and Seasonal Responses

The circadian—or biological—clock is an intrinsic, timekeeping, molecular mechanism that allows plants to coordinate physiological activities over 24-hour cycles called circadian rhythms. Photoperiodism is a collective term for the biological responses of plants to variations in the relative lengths of dark and light periods. The period of light-exposure is called the photoperiod.
Circadian Rhythms and Gene Regulation02:19

Circadian Rhythms and Gene Regulation

The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent years,...
Circadian Rhythms and Gene Regulation02:19

Circadian Rhythms and Gene Regulation

The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent years,...
Polarity of the Cytoskeleton01:18

Polarity of the Cytoskeleton

The intrinsic polarity of cells can be primarily attributed to two factors- i) the asymmetric accumulation of mobile components such are regulatory molecules and subcellular components across the cell and ii) the orientation of polar cytoskeletal filaments that make up the cytoskeletal networks, specifically microfilaments, and microtubules arranged along the axis of polarity. Interactions between the cytoskeletal filaments are crucial for the establishment and maintenance of the polar nature...
Circular Orbits and Critical Velocity for Satellites01:16

Circular Orbits and Critical Velocity for Satellites

The Moon orbits around the Earth. In turn, the Earth (and other planets) orbit the Sun. The space directly above our atmosphere is filled with artificial satellites in orbit. One can examine the circular orbit, the simplest kind of orbit, to understand the relationship between the speed and the period of planets and satellites with respect to their positions and the bodies that they orbit.
Nicolaus Copernicus (1473-1543) first suggested that the Earth and all other planets orbit the Sun in...
M-Cdk Drives Transition Into Mitosis02:15

M-Cdk Drives Transition Into Mitosis

Checkpoints throughout the cell cycle serve as safeguards and gatekeepers, allowing the cell cycle to progress in favorable conditions and slow or halt it in problematic ones. This regulation is known as the cell cycle control system.
Cyclin-dependent kinases, or Cdks, work in concert with cyclins to control cell cycle transitions. M-Cdk, a complex of Cdk1 bound to M cyclin, is a well-known example of this coordinated control that drives the transition from the G2 to the M phase.
M cyclin...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mechanical coordination between anaphase A and B drives asymmetric chromosome segregation.

bioRxiv : the preprint server for biology·2025
Same author

Mechanical coordination between anaphase A and B drives asymmetric chromosome segregation.

The Journal of cell biology·2025
Same author

An interkinetic envelope surrounds chromosomes between meiosis I and II in C. elegans oocytes.

The Journal of cell biology·2024
Same author

Investigating the consequences of chronic short sleep for metabolism and survival of oxidative stress.

bioRxiv : the preprint server for biology·2024
Same author

Cell type-specific regulation by different cytokinetic pathways in the early embryo.

microPublication biology·2024
Same author

An interkinetic envelope surrounds chromosomes between meiosis I and II in <i>C. elegans</i> oocytes.

bioRxiv : the preprint server for biology·2024
Same journal

A pan-vertebrate signaling motif controls the molecular function of intracellular AQP12.

The Journal of cell biology·2026
Same journal

Synergistic assembly, disassembly, and protection of complex forms of bundled F-actin.

The Journal of cell biology·2026
Same journal

Recruitment and release of XPG during NER is controlled by pre- and post-incision factors and EXO1.

The Journal of cell biology·2026
Same journal

Meiotic CENP-C supports centromere assembly and kinetochore recruitment in spermatogenesis.

The Journal of cell biology·2026
Same journal

Phosphatidylserine and RhoB connect PI4P and PA metabolism to maintain plasma membrane identity.

The Journal of cell biology·2026
Same journal

PIKfyve influences inter-organelle contacts with lysosomes to modulate the endoplasmic reticulum.

The Journal of cell biology·2026
See all related articles

Related Experiment Video

Updated: Jun 17, 2026

Spatiotemporal Analysis of Cytokinetic Events in Fission Yeast
11:19

Spatiotemporal Analysis of Cytokinetic Events in Fission Yeast

Published on: February 20, 2017

Cytokinetic astralogy.

Julie C Canman1

  • 1Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92037, USA. jcanman@ucsd.edu

The Journal of Cell Biology
|December 17, 2009
PubMed
Summary
This summary is machine-generated.

Cell division plane positioning is not always dependent on direct contact. Spindle microtubules can guide cell division from a distance, challenging previous assumptions in cell biology.

More Related Videos

Visualizing and Analyzing Intracellular Transport of Organelles and Other Cargos in Astrocytes
07:19

Visualizing and Analyzing Intracellular Transport of Organelles and Other Cargos in Astrocytes

Published on: August 28, 2019

Studying Mitotic Checkpoint by Illustrating Dynamic Kinetochore Protein Behavior and Chromosome Motion in Living Drosophila Syncytial Embryos
13:59

Studying Mitotic Checkpoint by Illustrating Dynamic Kinetochore Protein Behavior and Chromosome Motion in Living Drosophila Syncytial Embryos

Published on: June 14, 2012

Related Experiment Videos

Last Updated: Jun 17, 2026

Spatiotemporal Analysis of Cytokinetic Events in Fission Yeast
11:19

Spatiotemporal Analysis of Cytokinetic Events in Fission Yeast

Published on: February 20, 2017

Visualizing and Analyzing Intracellular Transport of Organelles and Other Cargos in Astrocytes
07:19

Visualizing and Analyzing Intracellular Transport of Organelles and Other Cargos in Astrocytes

Published on: August 28, 2019

Studying Mitotic Checkpoint by Illustrating Dynamic Kinetochore Protein Behavior and Chromosome Motion in Living Drosophila Syncytial Embryos
13:59

Studying Mitotic Checkpoint by Illustrating Dynamic Kinetochore Protein Behavior and Chromosome Motion in Living Drosophila Syncytial Embryos

Published on: June 14, 2012

Area of Science:

  • Cell Biology
  • Cytokinesis
  • Mitosis

Background:

  • Cell division plane specification traditionally involves direct interaction between mitotic spindle microtubules and the cell cortex.
  • This interaction was thought to be essential for accurate positioning of the cleavage furrow.

Purpose of the Study:

  • To investigate whether spindle microtubules can influence the division plane positioning without direct physical contact with the cell cortex.
  • To challenge the established model of division plane specification.

Main Methods:

  • Utilized live-cell imaging techniques.
  • Manipulated spindle-cortex interactions in animal cells.

Main Results:

  • Demonstrated that spindle microtubules can effectively determine the position of the cell division plane even when separated from the cell cortex.
  • Showcased a mechanism for division plane positioning that operates at a distance.

Conclusions:

  • The established model requiring direct microtubule-cortex contact for division plane specification is not universally applicable.
  • Cell division can be precisely controlled by signals transmitted from microtubules to the cortex over a distance, suggesting novel regulatory mechanisms in cytokinesis.