Related Experiment Video
Updated: Jun 17, 2026
06:09
An In Ovo Model for Testing Insulin-mimetic Compounds
Published on: April 23, 2018
Comparative field evaluations of in ovo applied technology
1Pfizer Animal Health, 1040 Swabia Court, Research Triangle Park, NC 27703, USA. christopher.williams2@pfizer.com
Poultry Science
|December 17, 2009
Summary
In ovo vaccination systems for poultry were compared in a hatchery setting. The Embrex Inovoject System demonstrated a higher hatch percentage, particularly at 18 days of in ovo transfer.
Area of Science:
- Poultry Science
- Animal Health Technology
- Hatchery Management
Background:
- In ovo vaccination is a key advancement in poultry mass vaccination, with commercial systems widely adopted in the US broiler industry.
- Continued evaluation of commercial in ovo vaccination systems is crucial for optimizing hatchery operations and animal welfare.
- Two major US-manufactured in ovo systems, Embrex Inovoject and Intelliject, are central to current industry practices.
Purpose of the Study:
- To compare the performance of two leading US-manufactured in ovo vaccination systems (Embrex Inovoject and Intelliject) under field conditions.
- To evaluate the impact of transfer day (day 18 vs. day 19) on the efficacy of these in ovo vaccination systems.
- To assess differences in system performance based on flock age and day of in ovo transfer.
Main Methods:
- A whole hatchery approach was employed to evaluate the two in ovo systems.
- Paired testing in a field setting allowed for direct comparison of the Embrex Inovoject System and Intelliject.
- Performance was assessed based on percentage of hatch and hatchability at specific days of in ovo transfer.
Main Results:
- The Embrex Inovoject System showed a significant advantage in percentage of hatch, up to 2.32%, at day 18 and 19 transfers in the whole hatchery study.
- Paired testing revealed a statistical difference favoring the Embrex Inovoject System for hatchability at day 18 of transfer.
- No significant difference in hatchability was observed between the systems at day 19 of transfer during paired testing.
Conclusions:
- The Embrex Inovoject System demonstrated superior performance in terms of hatch percentage compared to the Intelliject system under specific field conditions.
- The day of in ovo transfer (day 18 vs. day 19) significantly influenced the comparative performance of the evaluated systems.
- Further research and understanding of in ovo vaccination system performance are essential for advancing poultry production efficiency and health.
Related Concept Videos
01:16In vitro Mutagenesis
To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
01:17Equivalence: In Vitro and In Vivo Bioequivalence
Bioequivalence studies are crucial in evaluating whether new drugs can match an approved one regarding pharmacological effects and clinical performance. These studies test if drugs, despite different dosage forms, share identical plasma concentration-time profiles. Three types of equivalence are central to these studies: chemical, pharmaceutical, and therapeutic. Chemical equivalence indicates that two or more drug products contain identical active ingredients in equal amounts. Pharmaceutical...
01:59Plant Breeding and Biotechnology
Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.
01:24In Vitro Fertilization
In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
01:10In Vitro Drug Release Testing: Overview, Development and Validation
In vitro dissolution and drug release tests assess how quickly and how much of a drug is released from its dosage form into an aqueous medium under standardized laboratory conditions. These tests are essential tools in pharmaceutical development and quality assurance, offering insight into the drug's performance before clinical use.During formulation development, dissolution testing identifies incomplete or inconsistent drug release issues. It also supports decisions on selecting the optimal...
01:16In-vitro Mutagenesis
To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.