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Updated: Jun 17, 2026

Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock
Published on: June 6, 2011
Wunderlich's syndrome and hemorrhagic shock.
Massimo Medda1, Stefano Cm Picozzi, Giorgio Bozzini
1Urology Department, IRCCS Policlinico San Donato, University of Milan, San Donato Milanese, Milan, Italy.
Wunderlich's syndrome, a rare condition, can cause life-threatening bleeding. Selective arterial embolization effectively treated a case of massive retroperitoneal hemorrhage from renal angiomyolipoma in an obese patient.
Area of Science:
- Nephrology
- Vascular Surgery
- Radiology
Background:
- Wunderlich's syndrome involves spontaneous retroperitoneal hemorrhage, often linked to renal pathologies.
- Renal angiomyolipomas are benign tumors that can rupture and cause significant bleeding.
- Obesity is a potential contributing factor in complex cases.
Purpose of the Study:
- To present a case of Wunderlich's syndrome in an obese patient with massive retroperitoneal hemorrhage.
- To highlight the efficacy of selective arterial embolization in managing such critical events.
Main Methods:
- Case report of an obese woman diagnosed with Wunderlich's syndrome.
- Hemodynamic stabilization achieved through selective arterial embolization of the bleeding renal angiomyolipoma.
Main Results:
- Successful embolization led to stable hemodynamic patient condition.
- Demonstrated the effectiveness of interventional radiology in managing acute hemorrhage.
Conclusions:
- Selective arterial embolization is a crucial, effective treatment for ruptured renal angiomyolipomas causing Wunderlich's syndrome.
- This minimally invasive technique offers a high success rate, especially in life-threatening hemorrhage scenarios.
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