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Updated: Jun 17, 2026

Confocal Microscopy Analysis of Protein Sorting to Plasmodesmata in Nicotiana benthamiana
Published on: November 1, 2024
Plant PRA plays an important role in intracellular vesicular trafficking between compartments as GDF
Jeong Dong Bahk1, Woo Young Bang, Jae Bok Heo
1Division of Applied Life Science (BK21-EBNCRC), Graduate School of Gyeongsang National University, Jinju, Korea. jdbahk@gnu.ac.kr
Abstract:
Rab GTPases like Ras-related monomeric GTPases are well known to regulate intracellular vesicle trafficking by cycling between membrane-bound and cytosolic states. The functions of these proteins are controlled by upstream regulators and downstream effectors. Ypt/Rabs transmit signals to downstream effectors in a GTP-dependent manner. GDP-bound Rab proteins are extracted from their target membrane by cytosolic proteins known as GDP dissociation inhibitors (GDIs), and the Rab GTPase is recruited to the membrane compartment following dissociation from the GDI by GDI displacement factor (GDF). Now, we're going to discuss the role of plant PRA concerted with Rab and GDI proteins by recycling Rab between membrane and cytosol for intracellular trafficking of cargo proteins.
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