Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Cyclic stretch regulates immune responses via tank-binding kinase 1 expression in macrophages.

FEBS open bio·2022

Same author

Keloidal dermatofibroma: Clinicopathological comparison of 52 cases with a series of 2077 other dermatofibromas.

The Journal of dermatology·2022

Same author

Does noncontact phased-array ultrasound promote hair regrowth?

Journal of dermatological science·2022

Same author

Objective Odor Assessment in Patients with Osmidrosis.

Plastic and reconstructive surgery. Global open·2022

Same author

Discussion: Tear Trough Ligament Release and Autologous Fat Injection as a New Method for Tear Trough Deformity Correction.

Aesthetic plastic surgery·2022

Same author

A Scoring System That Predicts Difficult Lipoma Resection: Logistic Regression and Tenfold Cross-Validation Analysis.

Dermatology and therapy·2022

Search research articles

Related Experiment Video

Updated: Jun 17, 2026

Isolation, Culture, and Characterization of Primary Dermal Fibroblasts from Human Keloid Tissue

Isolation, Culture, and Characterization of Primary Dermal Fibroblasts from Human Keloid Tissue

Published on: July 28, 2023

Visual and pathologic analyses of keloid growth patterns.

Satoshi Akaishi¹, Rei Ogawa, Hiko Hyakusoku

¹Department of Plastic, Reconstructive and Aesthetic Surgery, Nippon Medical School Hospital, Tokyo, Japan. redstoneqq@yahoo.co.jp

Annals of Plastic Surgery

|December 17, 2009

Summary

This summary is machine-generated.

Irregularly shaped keloids are linked to severe infection or prior surgery. In contrast, keloid shape is primarily determined by skin tension when infection and surgical history are absent.

More Related Videos

Quantification of Strain in a Porcine Model of Skin Expansion Using Multi-View Stereo and Isogeometric Kinematics

Quantification of Strain in a Porcine Model of Skin Expansion Using Multi-View Stereo and Isogeometric Kinematics

Published on: April 16, 2017

Related Experiment Videos

Last Updated: Jun 17, 2026

Isolation, Culture, and Characterization of Primary Dermal Fibroblasts from Human Keloid Tissue

Isolation, Culture, and Characterization of Primary Dermal Fibroblasts from Human Keloid Tissue

Published on: July 28, 2023

Quantification of Strain in a Porcine Model of Skin Expansion Using Multi-View Stereo and Isogeometric Kinematics

Quantification of Strain in a Porcine Model of Skin Expansion Using Multi-View Stereo and Isogeometric Kinematics

Published on: April 16, 2017

Area of Science:

Dermatology
Pathology
Surgical Science

Background:

Keloids exhibit unique growth patterns, extending beyond original wound boundaries, unlike hypertrophic scars.
Clinical observations reveal both regular and irregular keloid shapes, with limited study on atypical growth characteristics.

Purpose of the Study:

To investigate the visual and pathological characteristics of irregularly shaped keloids.
To identify potential factors contributing to atypical keloid morphology.

Main Methods:

Surgical removal and visual analysis of 220 keloid specimens, classifying them into regular (R) and irregular (IR) shape groups.
Histological examination of keloid specimens for infection and review of patient history for previous keloidectomy and recurrence.

Main Results:

The irregular keloid group (IR) showed significantly higher rates of infection (46.9%) and prior keloidectomy (37.5%) compared to the regular keloid group (R) (1.9% and 1.3%, respectively).
Mean age in the IR group (45.27 years) was higher than in the R group (33.68 years).

Conclusions:

Severe infection and surgical history are identified as potential causes for the development of irregularly shaped keloids.
In the absence of significant infection or surgical history, intrinsic skin tension appears to be the primary determinant of keloid shape.