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A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis
Published on: March 8, 2022
Melanoma molecular subtypes: unifying and paradoxical results
Nancy E Thomas1, Peter A Kanetsky, Colin B Begg
1Department of Dermatology, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, USA. nthomas@med.unc.edu
The Journal of Investigative Dermatology
|December 17, 2009
Abstract
None:
In this issue, Hacker and colleagues provide further evidence that molecular subtypes of malignant melanoma may develop along divergent pathways. The authors did not find an association between somatic BRAF-mutant melanoma and germline melanocortin-1 receptor (MC1R) gene status. We discuss this seeming paradox in light of previous studies demonstrating strong associations.

