Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hydration in severe acute asthma.

P C Potter1, M Klein, E G Weinberg

  • 1Department of Clinical Science and Immunology, University of Cape Town, South Africa.

Archives of Disease in Childhood
|February 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Allergy Clinic: 50 years.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2006
Same author

Randomised controlled trial of the efficacy of a metered dose inhaler with bottle spacer for bronchodilator treatment in acute lower airway obstruction.

Archives of disease in childhood·2006
Same author

Childhood atopic eczema consensus document.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2005
Same author

Socioeconomic status and prevalence of allergic rhinitis and atopic eczema symptoms in young adolescents.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology·2004
Same author

Acute and maintenance treatment of atopic dermatitis in children - two comparative studies with fluticasone propionate (0.05%) cream.

The Journal of dermatological treatment·2003
Same author

Egg allergy and MMR vaccination.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2003
Same journal

Protecting adolescent confidentiality in the digital age: a global call for adolescent-informed electronic health records.

Archives of disease in childhood·2026
Same journal

Diagnostic accuracy study assessing the ability of paediatric asthma scores to predict admission following initial emergency department bronchodilator therapy: a Clinical Asthma Scoring systems in Paediatric Emergency (CASPER) study.

Archives of disease in childhood·2026
Same journal

Artificial intelligence for child health: current capabilities and the next frontier.

Archives of disease in childhood·2026
Same journal

Troubled origins and lasting impact of the first insulin injection.

Archives of disease in childhood·2026
Same journal

Paediatric readiness assessment tools in emergency care: a scoping review.

Archives of disease in childhood·2026
Same journal

Building a paediatric workforce to deliver the NHS prevention agenda: time for paediatric public health medicine?

Archives of disease in childhood·2026
See all related articles

Mild dehydration is common in children with severe acute asthma, with body weight typically near their stable levels. Bedside assessments of dehydration were unreliable in this study.

Area of Science:

  • Pediatrics
  • Respiratory Medicine
  • Clinical Nutrition

Background:

  • Severe acute asthma in children can lead to dehydration.
  • Accurate assessment of dehydration is crucial for effective management.
  • Previous studies have not fully characterized dehydration in pediatric asthma exacerbations.

Purpose of the Study:

  • To quantify the degree of dehydration in children admitted to the hospital for severe acute asthma.
  • To evaluate the reliability of bedside assessments for dehydration.
  • To identify clinical indicators correlating with dehydration severity.

Main Methods:

  • Studied twenty children during severe acute asthma attacks.
  • Measured body weight on admission compared to stable weight (7-10 days post-attack).

Related Experiment Videos

  • Assessed packed cell volume, serum electrolytes, and osmolality.
  • Correlated dehydration indicators with blood pH and peak expiratory flow rate recovery.

    • Main Results:

    • Mean body weight on admission was 97.8% of stable weight; only 3 children <95%.
    • Bedside dehydration assessment was unreliable.
    • Packed cell volume was significantly higher on admission (0.44 vs 0.42).
    • Dehydration correlated best with a fall in blood pH; no association with recovery of peak expiratory flow rate.

    Conclusions:

    • Mild dehydration is common in severe acute childhood asthma.
    • Fluid administration of 50 ml/kg/24 hours was found to be safe and appropriate.
    • Further research may be needed to refine dehydration assessment methods in pediatric asthma.