Acute intestinal pseudo-obstruction (Ogilvie's syndrome)
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Updated: Jun 17, 2026

A Mouse Model of Intestinal Partial Obstruction
Published on: March 5, 2018
1Department of Surgery, Eastern Virginia Medical School, Norfolk, Virginia, USA.
Abstract:
Acute colonic pseudo-obstruction (ACPO), also known as Ogilvie's syndrome, is a condition characterized by massive colonic distension in the absence of mechanical obstruction. Patients presenting with Ogilvie's syndrome have underlying medical and surgical conditions predisposing them to the syndrome. Ogilvie's syndrome can often be managed by conservative therapy. However, unrecognized and untreated, the continued distension associated with Ogilvie's syndrome can lead to perforation that is associated with a high mortality rate. In this article, the pathophysiology, epidemiology, and treatment options are reviewed.
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