Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 17, 2026

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates
06:10

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates

Published on: August 23, 2022

Biliary atresia.

C K Sinha1, Mark Davenport

  • 1Department of Pediatric Surgery, King's College Hospital, Denmak Hill, London SE5 9RS UK.

Journal of Indian Association of Pediatric Surgeons
|December 17, 2009
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

Cholecystitis01:20

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preface to topic collection: biliary atresia.

World journal of pediatric surgery·2026
Same author

Quality of care received by children with suspected appendicitis in the UK National Health Service.

Anaesthesia·2026
Same author

Pediatric cholecystectomy practices and training: an International Multicenter Survey by the European Union of Medical Specialists (UEMS) Section of Paediatric Surgery.

Pediatric surgery international·2026
Same author

Type 1 Congenital Pulmonary Airway Malformation: Diagnostic Accuracy of Radiological Features.

Pediatric pulmonology·2026
Same author

Ethical and legal challenges of integrating artificial intelligence into paediatric surgery.

Annals of the Royal College of Surgeons of England·2026
Same author

Serum aspartate aminotransferase to platelet ratio index in relation to liver histopathology of biliary atresia.

Journal of pediatric gastroenterology and nutrition·2026
Same journal

Epidemiology and Seasonal Trends of Pediatric Burns in North India: A Retrospective Study from a Tertiary Care Center.

Journal of Indian Association of Pediatric Surgeons·2026
Same journal

Variations in the Level of Termination and Characteristics of Tracheoesophageal Fistula in Patients with Type C Esophageal Atresia.

Journal of Indian Association of Pediatric Surgeons·2026
Same journal

Managing High Exudate Wounds: Improvised Negative Pressure Wound Therapy in Clostridial Infection.

Journal of Indian Association of Pediatric Surgeons·2026
Same journal

To Assess the Effect of Intraperitoneal Cut Suture Ends in Pediatric Minimally Invasive Surgery - A Study in Wistar Rats.

Journal of Indian Association of Pediatric Surgeons·2026
Same journal

Expanding the Genetic Blueprint of Wilms Tumor: An Account of 71 Novel Variants across 16 Genes with Novel Implications for Wilms Tumor Pathogenesis.

Journal of Indian Association of Pediatric Surgeons·2026
Same journal

Lingual Foregut Duplication Cyst - A Diagnostic and Therapeutic Challenge.

Journal of Indian Association of Pediatric Surgeons·2026
See all related articles

Biliary atresia (BA) is a serious liver disease where bile ducts are destroyed. The Kasai operation offers a chance for recovery, with about 60% of infants clearing jaundice and 40-65% surviving with their native liver.

Area of Science:

  • Pediatric Gastroenterology
  • Hepatology
  • Surgical Innovation

Background:

  • Biliary atresia (BA) is a severe cholangiodestructive disease leading to cirrhosis and liver failure.
  • Incidence varies globally, with higher rates in Asian countries.
  • Associated congenital anomalies define Biliary Atresia Splenic Malformation (BASM) syndrome.

Purpose of the Study:

  • To outline the etiology, diagnosis, and management of biliary atresia.
  • To describe the surgical approach and outcomes of the Kasai operation.
  • To highlight the role of liver transplantation as a second-stage treatment.

Main Methods:

  • Diagnosis involves ultrasonography, liver function tests, viral serology, and liver biopsy.
  • Classification is based on the level of extrahepatic duct obliteration (Types I, III).
Keywords:
Biliary atresiasurgical jaundice

Related Experiment Videos

Last Updated: Jun 17, 2026

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates
06:10

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates

Published on: August 23, 2022

  • Management includes the Kasai operation (portoenterostomy) followed by potential liver transplantation.

    • Main Results:

    • The Kasai operation aims to restore bile flow and prevent progression to cirrhosis.
    • Post-Kasai, approximately 60% of infants achieve jaundice clearance.
    • Five-year survival with native liver ranges from 40% to 65%.

    Conclusions:

    • Biliary atresia requires timely intervention to prevent irreversible liver damage.
    • The Kasai operation is the primary surgical treatment, with variable success rates.
    • Liver transplantation remains crucial for cases unresponsive to or complicated by the Kasai procedure.