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Updated: Jun 17, 2026

Forward Genetic Approaches in Chlamydia trachomatis
Published on: October 23, 2013
Host genetic studies in human ocular Chlamydial infection
A Natividad-Sancho1, M J Holland, D C W Mabey
1London School of Hygiene and Tropical Medicine, London University, London WC1E 7HT, UK.
Abstract:
Several human and animal models and methods have been used to dissect genetic contributions to immunity and pathogenesis of chlamydial diseases. Considerable achievements have been made in this field of host genetics. The hope is that these studies will lead to medical applications by helping to elicit the function of genes that are involved in host defense against chlamydia and in progression to severe sequelae. In the present article, we review a selection of findings in the forward genetics of ocular Chlamydia trachomatis infection in humans.
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