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Related Concept Videos

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Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
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Pneumothorax-II

Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
Esophageal Perforation-II: Clinical Manifestations and Management01:28

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Veins of Thorax01:19

Veins of Thorax

The azygos system is a crucial part of the body's circulatory system and drains most of the thorax. It comprises the azygos, hemiazygos, and accessory hemiazygos veins.
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Related Experiment Video

Updated: Jun 17, 2026

A Model of Acute Lung Injury Following Visceral Ischemia-Reperfusion by Supra-Coeliac Aortic Cross Clamping in Rats
06:50

A Model of Acute Lung Injury Following Visceral Ischemia-Reperfusion by Supra-Coeliac Aortic Cross Clamping in Rats

Published on: August 15, 2025

Thoracic vasculitis presenting as surgical problems.

Michael Jansen1, Sheikh Saleh, Margot Bolster

  • 1Department of Histopathology, Cork University Hospital, Wilton, Cork, Eire, Ireland. jansmichael@gmail.com

Virchows Archiv : an International Journal of Pathology
|December 17, 2009
PubMed
Summary

This study highlights four vasculitis cases with rare features causing surgical issues. Histology and post-mortem exams are crucial for diagnosing unsuspected vasculitis, impacting patient management and prosthetic device follow-up.

Related Experiment Videos

Last Updated: Jun 17, 2026

A Model of Acute Lung Injury Following Visceral Ischemia-Reperfusion by Supra-Coeliac Aortic Cross Clamping in Rats
06:50

A Model of Acute Lung Injury Following Visceral Ischemia-Reperfusion by Supra-Coeliac Aortic Cross Clamping in Rats

Published on: August 15, 2025

Area of Science:

  • Rheumatology
  • Cardiovascular Pathology
  • Surgical Complications

Background:

  • Vasculitis can present with unusual clinical and pathological features.
  • Pulmonary hypertension and aortitis are serious manifestations of vasculitis.
  • Immune-mediated diseases often require aggressive immunosuppression.

Observation:

  • Two patients with pulmonary hypertension initially suspected as thrombo-embolic disease had vasculitis (Wegener's granulomatosis and giant cell arteritis).
  • Two patients with aortitis secondary to immune-mediated diseases (Cogan's syndrome and relapsing polychondritis) presented with surgical complications.
  • These cases occurred despite aggressive immunosuppression, challenging initial clinical assessments.

Findings:

  • Wegener's granulomatosis affected large pulmonary arteries post-embolectomy.
  • Giant cell arteritis involved small pulmonary arteries in a case of presumed thrombo-embolic disease.
  • Cogan's syndrome presented with descending aortitis and endocarditis, a rare occurrence.

Implications:

  • The findings underscore the importance of considering vasculitis in complex cardiovascular presentations.
  • Histopathology and post-mortem examinations are vital for accurate diagnosis of obscure vasculitis.
  • Clinical vigilance is necessary, especially when managing surgical prosthetic devices in immunosuppressed patients.