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Functional Calcium Imaging in Developing Cortical Networks
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Effects of extracellular calcium on the volley activity of entorhinal cortex neurons in neonatal rats: computer

M G Sheroziya1, A V Egorov

  • 1Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow, Russia. sherozia@yandex.ru

Neuroscience and Behavioral Physiology
|December 17, 2009
PubMed

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Calcium is an essential signaling molecule required for various cellular functions. Calcium pumps and ion channels on cell and organellar membranes, such as those on the endoplasmic reticulum (ER), regulate calcium concentrations inside the cell. They remain closed, keeping the cytosolic calcium levels low at a resting state.
Various transmembrane receptors, such as G protein-coupled receptors (GPCRs), elicit a response to extracellular signals by increasing cytosolic calcium. Activated GPCRs...