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The enigmatic roles of microglial versus neuronal progranulin in neurological disease

Jason L Eriksen1

  • 1Pharmacological and Pharmaceutical Science, University of Houston, Houston, TX 77204, USA. jeriksen@central.uh.edu

Acta Neuropathologica
|December 17, 2009
PubMed
Abstract

No abstract available in PubMed .

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Glia, or neuroglia, are vital support cells that assist neurons in their functions. The term "glia" originates from the Greek word for "glue," reflecting their role in holding the nervous system together. These cells can be categorized into six types: four in the central nervous system (CNS) and two in the peripheral nervous system (PNS).
The CNS glial cell includes the astrocytes, the oligodendrocytes, the microglia, and the ependymal cells.
Astrocytes are star-shaped glial cells that interact...