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Related Concept Videos

Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Inverse Trigonometric Functions01:29

Inverse Trigonometric Functions

Inverse trigonometric functions are fundamental mathematical tools that reverse the actions of standard trigonometric functions. While trigonometric functions map angles to ratios, inverse trigonometric functions perform the opposite operation by mapping a ratio back to its corresponding angle. These functions are essential in various applications, particularly in determining angles when given specific distances, such as calculating elevation angles in navigation and engineering.For a function...
Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
The Skin Microbiota01:27

The Skin Microbiota

The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...
Derivatives of Inverse Trigonometric Functions01:30

Derivatives of Inverse Trigonometric Functions

A ship tracking an approaching aircraft relies on geometric measurements to find out the aircraft’s position relative to the observer. By measuring the slant distance to the aircraft and the angle of elevation, the horizontal and vertical components of the distance can be obtained using trigonometric relationships. This geometric approach provides a basis for analyzing how the observed angle changes as the aircraft moves closer to the ship.To examine the mathematical behavior of the angle of...
The Intrinsic Apoptotic Pathway01:31

The Intrinsic Apoptotic Pathway

Internal cellular stress, such as cellular injury or hypoxia, triggers intrinsic apoptosis. The B-cell lymphoma 2 (Bcl-2) family of proteins are the primary regulators of the intrinsic apoptotic pathway. For example, during DNA damage, checkpoint proteins, such as Ataxia Telangiectasia Mutated (ATM protein) and Checkpoints Factor-2 (Chk2) proteins, are activated. These proteins phosphorylate p53 which further activates pro-apoptotic proteins, such as Bax, Bak, PUMA, and Noxa, and inhibits...

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European S2k guidelines for hidradenitis suppurativa/acne inversa part 2: Treatment.

Journal of the European Academy of Dermatology and Venereology : JEADV·2024
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Haptoglobin is an independent marker for disease severity and risk for metabolic complications in hidradenitis suppurativa: A prospective study.

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Systemic immune-inflammation biomarkers in psoriasis patients under interleukin 17A-inhibitor treatment.

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Complete blood collection-based systemic inflammation biomarkers for patients with hidradenitis suppurativa.

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[Hidradenitis suppurativa /acne inversa-surgical options, reconstruction and combinations with drug therapies-an update].

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Related Experiment Video

Updated: Jun 17, 2026

A Rat Model of Compound Acne
03:10

A Rat Model of Compound Acne

Published on: November 1, 2024

[Acne inversa].

F G Bechara1, W Hartschuh

  • 1Klinik für Dermatologie und Allergologie, Ruhr-Universität Bochum, Bochum, Deutschland. f.bechara@derma.de

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|December 17, 2009
PubMed
Summary

Acne inversa, a chronic inflammatory skin condition, causes painful nodules and scarring. While antibiotics offer temporary relief, radical surgery is the primary treatment for severe cases, though it remains a therapeutic challenge.

Area of Science:

  • Dermatology
  • Pathology

Context:

  • Acne inversa (hidradenitis suppurativa) is a chronic inflammatory condition affecting hair follicles.
  • It leads to significant functional limitations and psychological distress.
  • The disease presents with painful nodules, abscesses, fistulas, and scarring in advanced stages.

Purpose:

  • To summarize the current understanding of acne inversa.
  • To discuss its clinical presentation and impact.
  • To review existing and recommended treatment strategies.

Summary:

  • The exact etiology of acne inversa is not fully elucidated.
  • Conservative treatments like antibiotics provide only temporary symptom management.
  • Radical wide excision of affected areas is the preferred therapeutic approach for severe manifestations.

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Last Updated: Jun 17, 2026

A Rat Model of Compound Acne
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A Rat Model of Compound Acne

Published on: November 1, 2024

Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma
04:12

Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma

Published on: January 19, 2024

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
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Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid

Published on: September 27, 2024

Impact:

  • Acne inversa poses a significant therapeutic challenge despite available interventions.
  • Effective management strategies are crucial to improve patient quality of life.
  • Further research into the causes and novel treatments is warranted.